Characterized by its large sensor, advanced imaging capabilities, and modular design, the GFX 50S from Fujifilm is a unique medium format mirrorless camera that is highly versatile and distinctly portable. At the heart of the GFX camera system is the 43.8 x 32.9mm 51.4MP CMOS sensor, which pairs with the X-Processor Pro image processor to produce files with extremely wide dynamic range and high resolution, as well as notable sensitivity to ISO 12800 for working in difficult lighting conditions. The sensor's large form factor also achieves a unique three-dimensional look with especially smooth tonal and color transitions. Beyond this, the sensor and processor combination also avails the ability to work in a variety of aspect ratios common to traditional large and medium format film cameras, as well as the ability to shoot Full HD 1080p/30 video. As forward-thinking as the GFX 50S is, its use of film-camera inspired design imbues it with intuitive operation and the ability to apply the camera system to myriad styles and methods of image-making.

Complementing the imaging assets is a truly versatile physical design that champions multiple ways of working with the camera. A removable 3.69m-dot OLED electronic viewfinder can be used for high-resolution eye-level viewing, and can be paired with an optional tilt adapter to permit working with the finder from various working angles. Alternatively, the rear 3.2" 2.36m-dot touchscreen LCD features a three-way tilting design that supports working from high and low angles, even when shooting in the vertical orientation. Operability is further reinforced through the use of several dedicated dials for adjusting exposure settings, and a top LCD screen is also featured for quickly checking settings and exposure data. Additionally, the GFX 50S sports a magnesium alloy build that is both lightweight and durable, and is also dust- and weather-sealed, as well as freezeproof down to 14°F, for working in trying environmental conditions.